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• This is a cream – for topical (skin) use only.
• NEW! – Comes in NO MESS airless pump dispenser.
• Each pump pre-measured to deliver the same amount each time.
• Estriol and Estradiol in Estro500 are bio-identical to human estrogens
• NEW! - Formulation contains 80% estriol, 20% estradiol
• No prescription needed (sold as a cosmetic)
• Vaginal use is OK.

*Important* - Regarding Unopposed Estrogens:

What are the ingredients in Estro500?

There are two active ingredients: estriol and estradiol. Each pump contains approximately 1.0 mg of combined bio-identical human estrogens. 80% (or 0.8 mg) is estriol and 20% (0.2 mg) is estradiol. Estradiol is several times more potent than estriol.

What is airless dispenser?

This is very similar to the popular liquid soap dispensers. Just press down on the pump and out comes a pre-measured amount that dispenses the same amount each time. It is no mess and much easier to use than the old jars we used to have.

How often should I take Estro500?

Apply two pumps to a clean, dry area of skin at bedtime. This dose is equivalent to .500 mg of Premarin. Often this dose needs to be increased depending on the response to symptoms. Estro500 can easily be applied twice daily. You can also apply directly to the outer edge and inside the vagina.

Does Estro500 irritate the skin?

It is a cosmetic product and actually helps the skin. However, some people can develop a redness or irritation if the cream is always applied to the same area. It is best to rotate skin sites to minimize skin irritation.